Database

Startups

Main Industry
Biotechnology
Main Product/Service
SERAbody Platform
Briefly, Trican Biotechnology harvested and assembled tumor reactive B cell receptors sequences into our proprietary DART library ''Directed and Activated immune Response against Tumors/lesions''.
Next-gen sequencing revealed more than 200 billion binders from DART with fully-human immunogenetics after recombination. For discovery campaigns Trican applies our proprietary high-throughput selection SERA ''Serially Enriched Recombinant Antibodies'' methodology.



Binders or SERAbodies from DART library by Trican are selected based on diversity, specificity, developability, and finally affinity against targets of interest. ?Trican engineers can further format and characterize SERAbodies into IgG or multispecifics candidates with targeted functionalities for further clinical development.

?

Multiple patents have been granted based on SERAbodies raised by Trican.

DART
''Directed Activated immune Response against Tumors/lesions'' B-Cell Receptor Library
DART
SERA
''Serially Enriched Recombinant Antibodies'' High-Throughput Selection platform
Founded Year
2015
Unified Business No.
42631063
Status
Active
Number of Employees
20
Total Paid-in Capital
253,755,000 (NT$)
Year of establishment, company status, responsible person, paid-in capital amount, and registered address are sourced from the "Commerce Industrial Services Portal, Department of Commerce, Ministry of Economic Affairs.
Location of Company
Taiwan , New Taipei City
Introduction
Trican Biotechnology, founded in 2015, is designing antibodies based on in vitro and in silico tools for in vivo validation. Through open technology integration with our proprietary platform, Trican delivers differentiated antibodies to address disease setting across oncology, immunology, and ophthalmology.

?

We are actively partnering globally with antibody-drug conjugates (ADCs), drug delivery, and bispecific/multispecific innovators.



More ↓

Similar Companies

Taiwan Bio-Manufacturing Corporation

TBMC will leverage existing resources to integrate intelligent and smart platform to establish various biopharmaceuticals manufacturing facility.

Rephlmmune Biotechnology Inc.

RephImmune is pioneering a new frontier in cancer immunotherapy with its proprietary platform, Reconstitute-Immunity Antigen-Cell Engager (RACE). This cutting-edge technology is rooted in regeneration biology and is specifically designed to reprogram and rebuild the immune system to effectively target and eliminate solid tumors.

At the core of RACE is a sophisticated algorithmic framework developed by RephImmune, which enables the identification, reassembly, and regeneration of immune components. The platform begins with the selection of 150 promising protein candidates and expands into a vast library of over 500,000 synthetically engineered novel proteins. These proteins are carefully designed and verified for their ability to modulate immune responses and engage tumor-specific antigens.

What sets RephImmune apart is its capacity to reconstitute cellular immunity across 13 different types of immune cells, including various subsets of T cells and innate immune cells. Through this process, the company has developed a novel engineered RACE-T cell specifically designed to attack and destroy solid tumors.

Importantly, the RACE platform is AI-compatible, meaning it can be trained and optimized through machine learning models. This integration of computational biology and artificial intelligence allows for continuous improvement and personalization of immunotherapy strategies, making RephImmune’s approach not only innovative but also scalable and adaptive to future clinical challenges.